Neil Barraclough, 64, of Lahaina, a property manager, died Friday in Lahaina. Born in Waipahu, he is survived by brothers Yeikichi, Seicho, Laurence and Roy and sisters Kiyoko Uyehara and Sally Asato. Burial will be in Diamond Head Memorial Park. After a program there, a candlelight vigil will be held on the palace grounds.Ĭatholic services will be held Monday at Diamond Head Mortuary. Sunday at the Iolani Palace grounds and proceed to the Richards Street YWCA. He is survived by sisters Gladys Minchew, Abigail Puli, Veronica Morikawa and Malamalama Maunupau. He testified on native water rights before the state Legislature. In recent years, he became active in the sovereignty movement and was on the board of the Native Hawaiian Advisory Council. Maunupau taught the language as a volunteer at the Women's Community Correctional Center and Waiawa Correctional Facility and in various community programs. That was his lifelong goal, to learn first the secrets of the language. He taught language on the musical sound of how they spoke. He would seek out kupuna, and picked up the pattern of the way they spoke. Minchew said her uncle felt the traditional style of the Hawaiian language was being lost. Maunupau, who was fluent in the language and served as interpreter for Bishop Museum researchers. People would walk away and say, I'm not interested.' He'd still walk up to the next Hawaiian and try again. I remember walking with him and he would walk up to any Hawaiian, anytime, with no shame or fear, and ask ∝o you know your language, do you know your history?' He was rejected 95 percent of the time. He was concerned that people learn their language and culture long before the Hawaiian renaissance of the past 15 years. 6.Īnd Maunupau would just love that, said his niece Kuulei Minchew. Horizontal and vertical activity of rats.The Hawaiian language will be spoken when Hawaiian community members gather at a Sunday memorial for Thomas K. Of the peptides studied, only SD tended to increase the SDĭemonstrated similar, albeit less pronounced effects to DNSP-5 on DA metabolismĪnd gene expression. Lesioned substantia nigra (SN) which suggested that DNSP-5 had compensatory and neuroprotective properties.
DNSP-5 also increased theĮxpression of Gfra1 and Gfra2 in the nonlesioned striatum and The level of DA in the nonlesioned striatum. Rats with 6-OHDA-induced PD-like parkinsonism, and a study of the motorĪctivity of the rats in an “open field” test showed that DNSP-5 and SD elevated An analysis of the levels of dopamine (DA), noradrenaline (NA),ĥ-hydroxytriptamine (5-HT), an expression analysis of Gdnf and Gdnf receptor genes Gfra1, Gfra2, Gfra3, Gfra4, and Gfral in various regions of the brain of
Synthetic peptides Semax and dopamine neuron stimulating peptide (DNSP-5), andĪ new synthetic Semax-DNSP-5 hybrid peptide (SD) on the functioning of brain Therefore, in the present pilot study, we investigated the effects of the May be used as an etiological or at least a complementary therapy in PD.
Some studies show that the synthetic analogs of natural peptides Sustain or activate neuron plasticity to enable their survival and function inĭifficult environments and after violated homeostasis, is a promising approach Therapyīased on regulatory peptides, particularly neuroprotective peptides, which can It isĬharacterized by progressive degeneration of dopaminergic neurons in the SlominskyĦ-OHDA, Parkinson’s Disease, Semax, DNSP-5, Gene Expressionĭisease (PD) is the second most common severe neurodegenerative disorder. Synthetic Peptides Affect the Expression of Gdnf and Gdnf Receptors in Rats with 6-OHDA-Induced PD-Like ParkinsonismĪUTHORS: Elena V. (2001) GDNF Is a Major Component of Trophic Activity in DA-Depleted Striatum for Survival and Neurite Extension of DAergic Neurons. Nakajima, K., Hida, H., Shimano, Y., Fujimoto, I., Hashitani, T., Kumazaki, M., Sakurai, T.
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